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Symex CML500

The Symex CML 500 is a high-performance vacuum homogenizer mixer designed for producing demanding products in the pharmaceutical and cosmetics industries.

This system combines mixing, dispersing, homogenizing, heating, cooling, and vacuum processing in a closed unit, enabling precise and reproducible production—from pilot scale to industrial applications. Such systems are specifically engineered for complex processes with stringent quality requirements.

Technical Highlights of the Symex CML 500:

Tank
- Usable volume: approx. 500 liters
- Total volume: approx. 780 liters
- Minimum volume: approx. 125–160 liters
- Product space pressure range: -1 / +2 bar
- Product temperature: up to approx. 133 °C
- Heating jacket: up to +4 bar / 151 °C
- Design in accordance with AD 2000
- The tank is fully pressure and vacuum-resistant, ensuring safe operations under demanding conditions.

Agitator
- Anchor agitator with flow breakers
- Speed range: approx. 11–66 rpm
- Power: approx. 7.5 kW
- Frequency-controlled
- Designed for highly viscous products
- The agitator provides uniform mixing and optimal heat transfer.

Homogenizer
- Power: approx. 16–20 kW
- Speed: up to approx. 3,000 rpm
- High shear performance for fine dispersion
- Rotor/stator system
- The homogenizer ensures stable emulsions and reproducible product quality.

Vacuum System
- Operation under vacuum possible
- Liquid ring vacuum pump (external)
- Pressure and vacuum monitoring
- Vacuum operation significantly reduces air entrainment and improves product quality.

Heating & Cooling
- Double-walled vessel (2-zone heating)
- Precise temperature control
- Even heat distribution
- CIP system

Multiple CIP Connections
- Rotating spray heads (360°)
- Cleaning of the entire process chamber, including pipelines

Material Feed
- Direct suction of liquids and powders
- Feed into the homogenizer area
- Fast and low-loss processing
- These integrated feeding and circulation systems enable highly efficient process management.

Additional Equipment
- Hydraulic lid lifting device
- Multi-nozzle with several connection options
- Sight glass with double wiper
- Vessel lighting
- Dosing vessel (approx. 8 liters)
- Sampling valve
- Membrane and disc valves
- Circulation piping for homogenization and CIP

Control & Operation
The system features a modern operation concept:
- Touch panel control
- Adjustable speed and cycle times
- Process monitoring (pressure, temperature, speed)
- Automatic and manual operating modes
- Alarm and safety functions
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Advantages of the Symex CML 500
- Combination of all process steps in one unit
- High process reliability through enclosed design
- Reproducible and stable product quality
- Suitable for highly viscous and sensitive products
- Hygienic design (GMP-compliant)
- Flexible application for different batch sizes

Delivery & Handling
- Delivery ex works
- Turn-key project available (incl. commissioning)
- International shipping possible

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